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US SB501: Strategy for Public Health Preparedness and Response to Artificial Intelligence Threats

Introduced United States (Federal) · 2025–2026 session

Last verified Oct 10, 2026 · official bill text

SB501 · where it stands

1 of 5 steps complete
  1. Introduced Complete
  2. Passed first chamber
  3. Passed both chambers
  4. Enacted
  5. Effective
What do these statuses mean?
Introduced
Filed in the legislature; may be waiting for a committee hearing.
Passed a chamber
Approved by one or both chambers; awaiting further action.
Enacted
Signed into law, or became law without a signature or over a veto.
Effective date
The date the law says it takes effect. Once it has passed, the page shows "Effective" and the date. A court order can still block a law; if we know of one, the summary says so.
Dead / vetoed
Vetoed, failed, or the session ended without action.

In one paragraph

The federal S. 501 (Strategy for Public Health Preparedness and Response to Artificial Intelligence Threats) would require the HHS Secretary, within 180 days after enactment, to submit a strategy on public health preparedness and biodefense against misuse of AI that threatens national health security. Introduced February 10, 2025 and referred to the Senate HELP Committee; no further action.

Plain-English summary, written with AI assistance. The official text controls.

What it means for business

None yet: the bill is pending. No duties for businesses. It directs HHS to prepare a strategy on AI-enabled biological threats, consulting countermeasure developers and AI experts.

Key provisions

  1. Not later than 180 days after enactment the HHS Secretary, in consultation with stakeholders including developers of countermeasures and AI experts, shall prepare and submit to relevant committees a strategy for public health preparedness, response and biodefense addressing risks of misuse of AI that present a threat to national health security
  2. The strategy shall include a framework, the Secretary's duties, functions and preparedness goals with success metrics, identified capability gaps and strategies to address them
  3. It shall include strategies to mitigate, at a minimum, development of biological weapons and design of viruses and bacteria resistant to treatment, and other AI misuse risks the Secretary determines
  4. The Secretary shall make it available to the Senate HELP Committee, the House Energy and Commerce Committee and other committees in a manner that does not compromise national security
  5. Amends Public Health Service Act section 2811(b)(4)(D) so that federal responses addressed by the strategy are included in coordination of all-hazards emergency response
  6. The text sets no appropriations or penalties; introduced February 10, 2025 and referred to the Senate HELP Committee

Latest legislative action

Feb 10, 2025. Read twice and referred to the Committee on Health, Education, Labor, and Pensions.

Sponsors

NameRoleDistrict
D Sponsor SD-MA
R Sponsor SD-NC

Topics and industries

Affected industries

This page is general information, not legal advice. Summaries are AI-assisted and may contain errors; read the statute for the controlling text and talk to a lawyer about your situation. Full disclaimer · Report an error